skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site


Williams–Campbell syndrome: a case report

Case report

(6233) Total Article Views

Authors: Konoglou M, Porpodis K, Zarogoulidis P, Loridas N, Katsikogiannis N, Mitrakas A, Zervas V, Kontakiotis T, Papakosta D, Boglou P, Bakali S, Courcoutsakis N, Zarogoulidis K

Published Date January 2012 Volume 2012:5 Pages 41 - 44

Maria Konoglou1, Konstantinos Porpodis2, Paul Zarogoulidis2, Nikolaos Loridas1, Nikolaos Katsikogiannis3, Alexandros Mitrakas2, Vasilis Zervas2, Theodoros Kontakiotis2, Despoina Papakosta2, Panagiotis Boglou4, Stamatia Bakali5, Nikolaos Courcoutsakis6, Konstantinos Zarogoulidis2
1First Pulmonary Clinic, "G. Papanikolaou" General Hospital, Thessaloniki, Greece; 2Pulmonary Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Greece; 3Surgery Department (NHS), University General Hospital of Alexandroupolis, Greece; 4Pulmonary Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece; 5Microbiology Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece; 6Radiology Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece

Introduction: Williams–Campbell syndrome, also known as bronchomalacia, is a rare disorder characterized by a deficiency of cartilage in subsegmental bronchi, leading to distal airway collapse and bronchiectasis. There have been few reports about patients affected by saccular bronchiectasis, paracicatricial emphysema, and diminished cartilage. These are all characteristic of Williams–Campbell syndrome.
Case presentation: This report presents a 57-year-old woman with progressive dyspnea, cough, sputum production, and fever. The clinical and laboratory examination revealed that the patient had a respiratory infection due to bronchiectasis caused by Williams–Campbell syndrome, which was undiagnosed in the patient until then.
Conclusion: Although a rare syndrome, when patients' signs and symptoms include recurrent respiratory infections, bronchiectasis, productive cough, and dyspnea, Williams–Campbell syndrome should be included in the differential diagnosis.

Keywords: bronchietasis, Williams–Campbell syndrome, bronchomalacia

Post to:
Cannotea Citeulike Facebook LinkedIn Twitter


Other articles by Dr Paul Zarogoulidis

“Denervation” of autonomous nervous system in idiopathic pulmonary arterial hypertension by low-dose radiation: a case report with an unexpected outcome
“One-stop shop” spectral imaging for rapid on-site diagnosis of lung cancer: a future concept in nano-oncology
A case of typical pulmonary carcinoid tumor treated with bronchoscopic therapy followed by lobectomy
Abdominal wall endometrioma mimicking an incarcerated hernia: a case report
Attitudes of asthmatic and nonasthmatic children to physical exercise
Chronic eosinophilic pneumonia due to radiographic contrast administration: an orphan disease?
Clinical differences between H3N2 and H1N1 influenza 2012 and lower respiratory tract infection found using a statistical classification approach
Clinical differences between influenza A (H1N1) virus and respiratory infection between the two waves in 2009 and 2010
Clinical experimentation with aerosol antibiotics: current and future methods of administration
Clinical experimentation with aerosol antibiotics: current and future methods of administration [Corrigendum]
Community-acquired pneumonia due to Legionella pneumophila, the utility of PCR, and a review of the antibiotics used
Current surgical status of thyroid diseases
Difficult airway and difficult intubation in postintubation tracheal stenosis: a case report and literature review
Docetaxel-carboplatin in combination with erlotinib and/or bevacizumab in patients with non-small cell lung cancer
Fat embolism due to bilateral femoral fracture: a case report
Gastrointestinal stromal tumor mesenchymal neoplasms: the offspring that choose the wrong path
Health costs from hospitalization with H1N1 infection during the 2009–2010 influenza pandemic compared with non-H1N1 respiratory infections
Immunomodifiers in combination with conventional chemotherapy in small cell lung cancer: a Phase II, randomized study
Inhaled chemotherapy in lung cancer: future concept of nanomedicine
Intratumoral chemotherapy for lung cancer: re-challenge current targeted therapies
Measurement of exhaled alveolar nitrogen oxide in patients with lung cancer: a friend from the past still precious today
New dilemmas in small-cell lung cancer TNM clinical staging
Non-Hodgkin lymphoma and GIST: molecular pathways and clinical expressions
Occupational chemical burns: a 2-year experience in the emergency department
Pegylated liposomal doxorubicin in malignant pleural mesothelioma: a possible guardian for long-term survival
Pelvic schwannoma in the right parametrium
Pulmonary thromboendarterectomy after treatment with treprostenil in a chronic thromboembolic pulmonary hypertension patient: a case report
Serratia pneumonia presenting as hemoptysis in a patient with sarcoidosis: a case report
Successful application of extracorporeal membrane oxygenation due to pulmonary hemorrhage secondary to granulomatosis with polyangiitis
Successful management of an inadvertent excessive treprostinil overdose
The role of second-line chemotherapy in small cell lung cancer: a retrospective analysis
Vitamin D in asthma and future perspectives

Readers of this article also read:

  • Testimonials

    "I was impressed at the rapidity of publication from submission to final acceptance." Dr Edwin Thrower, PhD, Yale University.

  • MLA'14 -

    May 16–21, 2014