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Williams–Campbell syndrome: a case report
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Authors: Konoglou M, Porpodis K, Zarogoulidis P, Loridas N, Katsikogiannis N, Mitrakas A, Zervas V, Kontakiotis T, Papakosta D, Boglou P, Bakali S, Courcoutsakis N, Zarogoulidis K
Published Date January 2012
Volume 2012:5 Pages 41 - 44
|Received:||21 November 2011|
|Accepted:||12 December 2011|
|Published:||11 January 2012|
1First Pulmonary Clinic, "G. Papanikolaou" General Hospital, Thessaloniki, Greece; 2Pulmonary Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Greece; 3Surgery Department (NHS), University General Hospital of Alexandroupolis, Greece; 4Pulmonary Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece; 5Microbiology Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece; 6Radiology Department, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece
Introduction: Williams–Campbell syndrome, also known as bronchomalacia, is a rare disorder characterized by a deficiency of cartilage in subsegmental bronchi, leading to distal airway collapse and bronchiectasis. There have been few reports about patients affected by saccular bronchiectasis, paracicatricial emphysema, and diminished cartilage. These are all characteristic of Williams–Campbell syndrome.
Case presentation: This report presents a 57-year-old woman with progressive dyspnea, cough, sputum production, and fever. The clinical and laboratory examination revealed that the patient had a respiratory infection due to bronchiectasis caused by Williams–Campbell syndrome, which was undiagnosed in the patient until then.
Conclusion: Although a rare syndrome, when patients' signs and symptoms include recurrent respiratory infections, bronchiectasis, productive cough, and dyspnea, Williams–Campbell syndrome should be included in the differential diagnosis.
Keywords: bronchietasis, Williams–Campbell syndrome, bronchomalacia
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