Back to Journals » Clinical Interventions in Aging » Volume 4

Review

Update on duloxetine for the management of stress urinary incontinence

       

Authors Basu M, Duckett J

Published 27 November 2008 Volume 2009:4 Pages 25—30

DOI https://doi.org/10.2147/CIA.S4062

Review by Single anonymous peer review

Peer reviewer comments 3

Download Article [PDF] 


Maya Basu, Jonathan RA Duckett

Department of Obstetrics and Gynaecology, Medway Maritime Hospital, Gillingham, Kent, UK

Abstract: Duloxetine is a relatively balanced serotonin and noradrenaline reuptake inhibitor (SNRI), which is the first drug with widely proven efficacy to have been licensed for the medical treatment of women with stress urinary incontinence (SUI). Despite favorable results from randomized controlled trials, surgical management continues to be the mainstay of treatment for SUI. In this review we explore the pharmacology of duloxetine in the nervous system and lower urinary tract, and the evidence for its use in the management of women with urinary incontinence.

Keywords: duloxetine, stress urinary incontinence, overactive bladder

Creative Commons License © 2008 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]