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Therapeutics and Clinical Risk Management

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Editor in Chief Professor Garry Walsh

Emerging oral treatments in multiple sclerosis – clinical utility of cladribine tablets
Claudio Gasperini, Serena Ruggieri, Carlo Pozzilli

Selecting GLP-1 agonists in the management of type 2 diabetes: differential pharmacology and therapeutic benefits of liraglutide and exenatide
Jonathan Pinkney, Thomas Fox, Lakshminarayan Ranganath

Adult patients with pulmonary arterial hypertension due to congenital heart disease: a review on advanced medical treatment with bosentan
Mark J Schuuring, Jeroen C Vis, Marielle G Duffels, et al.

Molecular mechanisms and treatment strategies for Dupuytren’s disease
David B O’Gorman, Linda Vi, Bing Siang Gan

Current and emerging treatments for the management of osteogenesis imperfecta
Elena Monti, Monica Mottes, Paolo Fraschini, et al

Correlation of random urine protein creatinine (P-C) ratio with 24-hour urine protein and P-C ratio, based on physical activity: a pilot study
Seyed-Ali Sadjadi, Navin Jaipaul

Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis
Michael Pazianas, Cyrus Cooper, F Hal Ebetino, et al

Prevalence of impaired glucose tolerance and insulin resistance among obese children and adolescents
Robabeh Ghergherechi, Ali Tabrizi

Update on current and emerging treatment options for post-polio syndrome
Elisabeth Farbu

Optimal therapy in Gaucher disease
Ozlem Goker-Alpan

Analysis of factors influencing the overall effect of racecadotril on childhood acute diarrhea. Results from a real-world and post-authorization surveillance study in Venezuela
Jose Chacón

Critical appraisal of a fixed combination of esomeprazole and low dose aspirin in risk reduction
Ravi Vachhani, Doumit Bouhaidar, Alvin Zfass, et al

Antibiotic prescribing practices by dentists: a review
Najla Saeed Dar-Odeh, Osama Abdalla Abu-Hammad, Mahmoud Khaled Al-Omiri, et al

Review of mifamurtide in the treatment of patients with osteosarcoma
Leo Kager, Ulrike Pötschger, Stefan Bielack

Continuous epidural infusion of morphine versus single epidural injection of extended-release morphine for postoperative pain control after arthroplasty: a retrospective analysis
Stephanie Vanterpool, Randall Coombs, Karamarie Fecho

Investigation of clinical interaction between omeprazole and tacrolimus in CYP3A5 non-expressors, renal transplant recipients
Paraskevi F Katsakiori, Eirini P Papapetrou, Dimitrios S Goumenos, et al

Management of ANCA-associated vasculitis: Current trends and future prospects
Sally Hamour, Alan D Salama, Charles D Pusey

Serum glutathione transferase does not respond to indole-3-carbinol: A pilot study
Daniel R McGrath, Hamid Frydoonfar, Joshua J Hunt, et al

Intravitreal bevacizumab for macular edema due to proton beam radiotherapy: Favorable results shown after eighteen months follow-up
Eleni Loukianou, Dimitrios Brouzas, Eleni Georgopoulou, et al

Efficacy and safety of zoledronic acid in the treatment of glucocorticoid-induced osteoporosis
Ege Can Serefoglu, Zafer Tandogdu

Maximum opening of the mouth by mouth prop during dental procedures increases the risk of upper airway constriction
Hiroshi Ito, Hiroyoshi Kawaai, Shinya Yamazaki, et al

Role of saxagliptin as monotherapy or adjunct therapy in the treatment of type 2 diabetes
Morali D Sharma

Obesity is not associated with contrast nephropathy
Navin Jaipaul, Rendell Manalo, Seyed-Ali Sadjadi, et al

Equitable access to HCV care in HIV-HCV co-infection can be achieved despite barriers to health care provision
Curtis L Cooper, Celine Giordano, Dave Mackie, et al

Seven years’ experience with alendronate in postmenopausal Japanese women with osteoporosis
Jun Iwamoto, Yoshihiro Sato, Mitsuyoshi Uzawa, et al

Critical appraisal and clinical utility of atosiban in the management of preterm labor
Olaleye Sanu, Ronald F Lamont

Ropinirole in restless legs syndrome and periodic limb movement disorder
Daniel Erichsen, Raffaelle Ferri, David Gozal

Critical appraisal of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia
Ayman A Hussein, Stephen J Nicholls

Topical calcineurin inhibitors in systemic lupus erythematosus
Christos E Lampropoulos, David P D’Cruz

Risks vs benefits of glatiramer acetate: a changing perspective as new therapies emerge for multiple sclerosis
Kenneth P Johnson

Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis
Nora Koutruba, Jason Emer, Mark Lebwohl

Critical appraisal of tocilizumab in the treatment of moderate to severe rheumatoid arthritis
Linda L Hushaw, Ray Sawaqed, Ghaleb Sweis, et al

Update on dexmedetomidine: use in nonintubated patients requiring sedation for surgical procedures
Mohanad Shukry, Jeffrey A Miller

Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures
Martin E Brown, Rif S El-Mallakh

Abacavir/lamivudine combination in the treatment of HIV: a review
Geetha Sivasubramanian, Emmanuel Frempong-Manso, Rodger D MacArthur

Managing opioid-induced constipation in advanced illness: focus on methylnaltrexone bromide
Katri Elina Clemens, Eberhard Klaschik

Long-term maintenance of pediatric asthma: focus on budesonide/formoterol inhalation aerosol
Peter N Huynh, Lyne G Scott, Kenny YC Kwong

New approaches in the management of spasticity in multiple sclerosis patients: role of cannabinoids
Paul F Smith

Profile of etravirine for the treatment of HIV infection
Alice Tseng, Rodger D MacArthur

Tenofovir-associated bone density loss
Iwen F Grigsby, Lan Pham, Louis M Mansky, et al

A review of the applications of the hydrofiber dressing with silver (Aquacel Ag®) in wound care

Yoav Barnea, Jerry Weiss, Eyal Gur



Current and emerging treatment options for Graves’ hyperthyroidism
Prakash Abraham, Shamasunder Acharya

Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease
Suzanne Skoda-Smith, Troy R Torgerson, Hans D Ochs

Update on the efficacy, effectiveness and safety of artemether–lumefantrine combination therapy for treatment of uncomplicated malaria
Pauline Byakika-Kibwika, Mohammed Lamorde, Harriet Mayanja-Kizza, et al

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