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The occurrence of cerebrovascular atherosclerosis in Alzheimer’s disease patients
Authors Yuan, Wen G, li Y, Liu C
Received 18 February 2013
Accepted for publication 13 March 2013
Published 24 May 2013 Volume 2013:8 Pages 581—584
DOI https://doi.org/10.2147/CIA.S44160
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Jing Yuan,1,* Ge Wen,2,* Yingjia Li,3 Changxing Liu1
1Department of Medical Information, General Hospital of Jinan Military Command, Jinan, People’s Republic of China; 2Imaging Center, Nanfang Hospital of Southern Medical University, Guangzhou, People’s Republic of China; 3Ultrasound Diagnosis Department, Nanfang Hospital of Southern Medical University, Guangzhou, People’s Republic of China
*These authors contributed equally to this work
Background: Both Alzheimer’s disease (AD) and cerebrovascular atherosclerosis (CA) contributed to dementia in an aged population. Whether they share the same mechanism is unknown.
Aim: Our goal was to explore the occurrence rates of CA in AD patients.
Method: Here we examined the degree of CA in different groups of AD patients with contrast angiography. Ninety-three AD patients were recruited to the present study. Contrast computed tomography scanning and contrast angiography were performed for CA analyses.
Result: We found that the cerebrovascular plaques were common in AD patients, which was partly correlated with the severity of AD (as determined by cognitive decline).
Conclusion: We concluded that vascular dementia may partly correlate with AD pathology.
Keywords: Alzheimer’s disease, cerebrovascular atherosclerosis, aging, patients
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