Severe hepatotoxic adverse reaction in a healthy schoolgirl after treatment with flucloxacillin

Case report

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Authors: C-J Törnhage, G Brunlöf, S M Wallerstedt

Published Date March 2009 Volume 2009:1 Pages 17 - 19

DOI: http://dx.doi.org/10.2147/DHPS.S4316

C-J Törnhage¹, G Brunlöf², S M Wallerstedt²

¹Department of Paediatrics, Central Hospital, Skaraborg, Skövde, Sweden; ²Department of Clinical Pharmacology, Sahlgrenska University Hospital, Göteborg, Sweden

Abstract: This is the first detailed description of a severe hepatotoxic reaction in a previously healthy 9-year-old schoolgirl after ingestion of some flucloxacillin tablets. She was clinically well within one week and alanine aminotransferase in serum was normalized in one month. Follow up for more than one year was normal.

Keywords: adverse reaction, children, flucloxacillin, hepatopathy