Serum erythropoietin levels in patients with central serous chorioretinopathy

Original Research

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Authors: Burak Turgut, Nevin Ilhan, Fatma Yayla Uyar, et al

Published Date June 2010 Volume 2010:2 Pages 77 - 81

DOI: http://dx.doi.org/10.2147/EB.S10918

Burak Turgut¹, Nevin Ilhan², Fatma Yayla Uyar¹, Ulku Celiker¹, Tamer Demir¹, Suleyman Serdar Koca³

¹Fırat University School of Medicine, Department of Ophthalmology, Elazig, Turkey; ²Fırat University School of Medicine, Department of Biochemistry, Elazig, Turkey; ³Fırat University School of Medicine, Department of Interal Medicine, Elazig, Turkey

Objective: To evaluate the levels of erythropoietin (EPO) in the serum in patients with central serous chorioretinopathy (CSC).

Methods: An institutional comperative clinical study. The serum EPO levels were measured with the enzyme-linked immunosorbent assay (ELISA) method, of 15 patients with active CSC (Group 1), 15 patients with inactive CSC (Group 2) and 15 healthy volunteers (Group 3). Kruskal–Wallis variance analysis and Mann–Whitney U test were used for statistical analysis.

Results: The patient and control groups were matched for age and sex. There was no statistically significant variation with regard to age and gender among the groups (P > 0.05). The mean serum EPO concentrations in patients with active CSC (Group 1), inactive CSC (Group 2) and in healthy controls (Group 3) were 11.39 ± 3.01 mlU/mL, 11.79 ± 3.78 mlU/mL and 11.95 ± 3.27 mlU/mL, respectively. There was no significant variation among the serum EPO concentrations of the study groups (P > 0.05).

Conclusion: These findings suggest no role of serum EPO in pathogenesis of CSC.

Keywords: Central serous chorioretinopathy, erythropoietin, serum

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