skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8852

Recent achievements in the management of Raynaud’s phenomenon

Review

(3278) Views  (1258) Full article downloads

Authors: Magnus Baumhäkel, Michael Böhm

Published Date March 2010 Volume 2010:6 Pages 207 - 214
DOI: http://dx.doi.org/10.2147/VHRM.S5255

Magnus Baumhäkel, Michael Böhm

Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany

Abstract: Raynaud’s phenomenon is a clinical disorder with episodic digital ischemic vasospasm triggered by cold- or emotional-stress. It was first mentioned by Maurice Raynaud in 1862 describing “a local asphyxia of the extremities” and was further divided into primary Raynaud’s disease and secondary Raynaud’s phenomenon, which is often related to connective tissue diseases, but also physical or chemical strain. Though pathophysiology of Raynaud’s phenomenon is still poorly understood, systemic and local vascular effects are most likely to be involved in primary Raynaud’s disease. In secondary Raynaud’s phenomenon additional abnormalities in vascular structure and function may play the major role. Thus, medical treatment of Raynaud’s phenomenon remains unsatisfactory, due to limited understanding of pathophysiological mechanisms. This review addresses current evidence for medical treatment of primary and secondary Raynaud’s phenomenon with regard to pathophysiological mechanisms as well as future perspectives.

Keywords: Raynaud’s disease, mechanisms, treatment






 

Other articles by Dr Magnus Baumhäkel



Readers of this article also read:

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors
Berberine: metabolic and cardiovascular effects in preclinical and clinical trials
Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy
Advances in the treatment of Raynaud’s phenomenon
Does plasmin have anticoagulant activity?
Atorvastatin in stroke: a review of SPARCL and subgroup analysis
Mortality following operations for lower extremity peripheral arterial disease
Practical recommendations for treatment of hypertension in older patients
Impact of a diabetic foot care education program on lower limb amputation rate
COSEHC global vascular risk management quality improvement program: rationale and design
  • Join ISVH

    Be part of the World's leading experts in vascular health by joining the International Society of Vascular Health (ISVH)

  • Testimonials

    "... I was impressed at the rapidity of publication from submission to final acceptance." Dr Edwin Thrower, PhD, Yale University