Back to Browse Journals » Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy » Volume 4

Primary infragenicular angioplasty for diabetic neuroischemic foot ulcers following the angiosome distribution: a new paradigm for the vascular interventionist?

Authors Alexandrescu V, Hubermont G

Published Date August 2011 Volume 2011:4 Pages 327—336

DOI http://dx.doi.org/10.2147/DMSO.S23471

Published 22 August 2011

Vlad Alexandrescu1, Gerard Hubermont2
1Department of Vascular Surgery, Princess Paola Hospital, Marche- en-Famenne, Belgium; 2Department of Diabetology, Princess Paola Hospital, Marche-en-Famenne and Sainte-Thérèse Hospital, Bastogne, Belgium

Abstract: The angiosome principle was first described by Jan Taylor in 1987 in the plastic reconstructive surgery field, providing useful information on the vascular anatomy of the human body. Specifically concerning foot and ankle pathology, it may help the clinician to select better vascular access and specific strategies for revascularization. This knowledge may be particularly beneficial when treating diabetic neuroischemic foot wounds associated with particularly aggressive atherosclerotic disease and a poor collateral circulation. The implementation of angiosome-based strategies in diabetic infragenicular vascular reconstruction may afford encouraging wound healing and limb preservation rates using both bypass and endovascular techniques. The minimal invasiveness of these novel strategies enables us to perform more specific and more distal tibial and/or foot arterial reconstructions, in one or multiple targeted vessels. This paper reviews the available literature on this revascularization strategy and focuses on the potential benefit of angiosome-guided primary angioplasty for diabetic ischemic foot ulcers.

Keywords: critical limb ischemia, diabetic foot, limb salvage, angiosomes, angioplasty

Download Article [PDF] View Full Text [HTML] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php

Readers of this article also read:

Opioid rotation in patients initiated on oxycodone or morphine: a register study

Ericson L, Ambring A, Björholt I, Dahm P

Journal of Pain Research 2013, 6:379-386

Published Date: 20 May 2013

Preparation for high-acuity clinical placement: confidence levels of final-year nursing students

Porter J, Morphet J, Missen K, Raymond A

Advances in Medical Education and Practice 2013, 4:83-89

Published Date: 30 April 2013

Non-small cell lung cancer therapy: safety and efficacy in the elderly

Glotzer OS, Fabian T, Chandra A, Bakhos CT

Drug, Healthcare and Patient Safety 2013, 5:113-121

Published Date: 22 April 2013

Bevacizumab in high-grade gliomas: a review of its uses, toxicity assessment, and future treatment challenges

Rahmathulla G, Hovey EJ, Hashemi-Sadraei N, Ahluwalia MS

OncoTargets and Therapy 2013, 6:371-389

Published Date: 15 April 2013

Frequency of diabetes, impaired fasting glucose, and glucose intolerance in high-risk groups identified by a FINDRISC survey in Puebla City, Mexico

García-Alcalá H, Genestier-Tamborero CN, Hirales-Tamez O, Salinas-Palma J, Soto-Vega E

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2012, 5:403-406

Published Date: 19 November 2012

Alogliptin: a new addition to the class of DPP-4 inhibitors

Radha Andukuri, Andjela Drincic, Marc Rendell

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2009, 2:117-126

Published Date: 21 July 2009

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors

Eduardo Pimenta, Suzanne Oparil

Vascular Health and Risk Management 2009, 5:453-463

Published Date: 19 May 2009