skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8852

Potential of adult neural stem cells for cellular therapy

(3314) Views  (502) Full article downloads

Authors: Philippe Taupin

Published Date October 2007 Volume 2007:1(1) Pages 53 - 58
DOI: http://dx.doi.org/10.2147/BTT.S

Philippe Taupin

National Neuroscience Institute, Singapore, Singapore

Abstract: Cellular therapy is the replacement of unhealthy or damaged cells or tissues by new ones. Because neurodegenerative diseases, cerebral strokes, and traumatic injuries to the central nervous system (CNS) produce neurological deficits that result from neuronal loss, cell therapy is a prominent area of investigation for the treatment of neurological diseases and injuries. Neural progenitor and stem cells generate the main phenotyes of the nervous system, and offer a model of choice for cellular therapy in the CNS. With the confirmation that neurogenesis occurs in the adult brain, and the recent isolation and characterization in vitro of neural progenitor and stem cells from the adult CNS, new strategies are being devised and have the potential to treat a broad range of CNS diseases and injuries.

Keywords: neurogenesis, central nervous system, neurodegenerative diseases, trophic factors, regeneration, transplantation








Readers of this article also read:

Trastuzumab in the management of early and advanced stage breast cancer
α-L-iduronidase therapy for mucopolysaccharidosis type I
Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap)
Therapeutic vaccines for malignant brain tumors
Basiliximab induction therapy in kidney transplantation: Benefits for long term allograft function after 10 years?
Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency
Abatacept in difficult-to-treat juvenile idiopathic arthritis
Evidence-based decision-making within the context of globalization: A “Why–What–How” for leaders and managers of health care organizations
New and emerging treatment approaches to lupus
Proteasome inhibition and its therapeutic potential in multiple myeloma
  • Testimonials

    "... I was impressed at the rapidity of publication from submission to final acceptance." Dr Edwin Thrower, PhD, Yale University

  • Journal Indexing

    See where all the Dove Press journals are indexed