Back to Browse Journals » Patient Preference and Adherence » Volume 7

Nominal group technique to select attributes for discrete choice experiments: an example for drug treatment choice in osteoporosis

Authors Hiligsmann M, van Durme C, Geusens P, Dellaert BG, Dirksen CD, van der Weijden T, Reginster JY, Boonen A

Published Date February 2013 Volume 2013:7 Pages 133—139

DOI http://dx.doi.org/10.2147/PPA.S38408

Received 22 September 2012, Accepted 28 November 2012, Published 7 February 2013

Mickael Hiligsmann,1-3 Caroline van Durme,2 Piet Geusens,2 Benedict GC Dellaert,4 Carmen D Dirksen,3 Trudy van der Weijden,5 Jean-Yves Reginster,6 Annelies Boonen2

1Department of Health Services Research, School for Public Health and Primary Care (CAPHRI), Maastricht University, The Netherlands, 2Department of Internal Medicine, CAPHRI, Maastricht University, The Netherlands, 3Department of Clinical Epidemiology and Medical Technology Assessment, CAPHRI, Maastricht University, The Netherlands, 4Department of Business Economics, Erasmus Rotterdam University, The Netherlands, 5Department of General Practice, CAPHRI, Maastricht University, The Netherlands, 6Department of Public Health, Epidemiology and Health Economics, University of Liege, Belgium

Background: Attribute selection represents an important step in the development of discrete-choice experiments (DCEs), but is often poorly reported. In some situations, the number of attributes identified may exceed what one may find possible to pilot in a DCE. Hence, there is a need to gain insight into methods to select attributes in order to construct the final list of attributes. This study aims to test the feasibility of using the nominal group technique (NGT) to select attributes for DCEs.
Methods: Patient group discussions (4–8 participants) were convened to prioritize a list of 12 potentially important attributes for osteoporosis drug therapy. The NGT consisted of three steps: an individual ranking of the 12 attributes by importance from 1 to 12, a group discussion on each of the attributes, including a group review of the aggregate score of the initial rankings, and a second ranking task of the same attributes.
Results: Twenty-six osteoporotic patients participated in five NGT sessions. Most (80%) of the patients changed their ranking after the discussion. However, the average initial and final ranking did not differ markedly. In the final ranking, the most important medication attributes were effectiveness, side effects, and frequency and mode of administration. Some (15%) of the patients did not correctly rank from 1 to 12, and the order of attributes did play a role in the ranking.
Conclusion: The NGT is feasible for selecting attributes for DCEs. Although in the context of this study, the NGT session had little impact on prioritizing attributes, this approach is rigorous, transparent, and improves the face validity of DCEs. Additional research in other contexts (different decisional problems or different diseases) is needed to determine the added value of the NGT session, to assess the optimal ranking/rating method with control of ordering effects, and to compare the attributes selected with the different approaches.

Keywords: discrete choice experiment, nominal group technique, patient preference, medication attributes, osteoporosis

Download Article [PDF] View Full Text [HTML] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php

Readers of this article also read:

A review of minodronic acid hydrate for the treatment of osteoporosis

Tanishima S, Morio Y

Clinical Interventions in Aging 2013, 8:185-189

Published Date: 15 February 2013

Fabrication and characterization of nuclear localization signal-conjugated glycol chitosan micelles for improving the nuclear delivery of doxorubicin

Yu J, Xie X, Zheng M, Yu L, Zhang L, Zhao J, Jiang D, Che X

International Journal of Nanomedicine 2012, 7:5079-5090

Published Date: 21 September 2012

Cuprous oxide nanoparticles selectively induce apoptosis of tumor cells

Wang Y, Zi XY, Su J, Zhang HX, Zhang XR, Zhu HY, Li JX, Yin M, Yang F, Hu YP.

International Journal of Nanomedicine 2012, 7:2641-2652

Published Date: 28 May 2012

Intracellular heavy metal nanoparticle storage: progressive accumulation within lymph nodes with transformation from chronic inflammation to malignancy

Tommaso Iannitti, Stefania Capone, Antonietta Gatti, et al

International Journal of Nanomedicine 2010, 5:955-960

Published Date: 15 November 2010

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors

Eduardo Pimenta, Suzanne Oparil

Vascular Health and Risk Management 2009, 5:453-463

Published Date: 19 May 2009