-
Therapeutics and Clinical Risk Management
-
About Dovepress
Open access peer-reviewed scientific and medical journals.
-
Open Access
Dove Medical Press is now a member of the Open Access Initiative
-
An Author's Guide
A guide to help authors get their paper published.
-
Advocacy
Support Open Access and Dove Press
-
Reprints
Promotional Article Monitoring - further details
-
Favored Author Program
Real benefits for authors, including fast-track processing of papers.
New advances in the treatment of Clostridium difficile infection (CDI)
Review
(5302) Views (909) Full article downloads
Authors: Dennis D Hedge, Joe D Strain, Jodi R Heins, Debra K Farver
Published Date September 2008
Volume 2008:4(5) Pages 949 - 964
DOI: http://dx.doi.org/10.2147/TCRM.S3145
Dennis D Hedge, Joe D Strain, Jodi R Heins, Debra K Farver
South Dakota State University College of Pharmacy, Brookings, SD 57007, USA
Abstract: Clostridium difficile infections (CDI) have increased in frequency throughout the world. In addition to an increase in frequency, recent CDI epidemics have been linked to a hypervirulent C. difficile strain resulting in greater severity of disease. Although most mild to moderate cases of CDI continue to respond to metronidazole or vancomycin, refractory and recurrent cases of CDI may require alternative therapies. This review provides a brief overview of CDI and summarizes studies involving alternative antibiotics, toxin binders, probiotics, and immunological therapies that can be considered for treatment of acute and recurrent CDI in severe and refractory situations.
Keywords: Clostridium difficile, antibiotics, probiotics, immunological therapy
Other articles by Dr Debra Farver
Readers of this article also read:
Treatment of hereditary angioedema with plasma-derived C1 inhibitor
Weekly docetaxel in the treatment of metastatic breast cancer
Docetaxel in the treatment of squamous cell carcinoma of the head and neck
Periosteoplasty for covering gingival recessions: Clinical results
Using systematically observed clinical encounters (SOCEs) to assess medical students’ skills in clinical settings
Profile of ciclesonide for the maintenance treatment of asthma
Optimal management of Barrett's esophagus: pharmacologic, endoscopic, and surgical interventions
Helicobacter pylori infection and primary open-angle glaucoma: is there a connection?
Role of gabapentin enacarbil XR in restless legs syndrome
- Have an opinion about one of our articles?
We encourage you to write a Letter to the Editor
- American Acne and Rosacea Society
The American Acne and Rosacea Society (AARS), is a 501(c)(6) non-profit organization dedicated to elevating the understanding and treatment of acne and rosacea.
- The benefits and risks of testosterone replacement therapy: a review
- Tenofovir-associated bone density loss
- Drug design with Cdc7 kinase: a potential novel cancer therapy target
- Development of mucosal adjuvants for intranasal vaccine for H5N1 influenza viruses
