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Multifocal visual evoked potentials in amblyopia due to anisometropia

Original Research

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Authors: MM Moschos, I Margetis, S Tsapakis, et al

Published Date July 2010 Volume 2010:4 Pages 849 - 853
DOI: http://dx.doi.org/10.2147/OPTH.S11762

MM Moschos, I Margetis, S Tsapakis, G Panagakis, IK Chatzistephanou, E Iliakis
Department of Ophthalmology, University of Athens, Greece

Purpose: To investigate multifocal visual evoked potentials (mfVEP) of the amblyopic and fellow eye in amblyopia due to anisometropia.

Methods: We recorded mfVEP in both eyes of 15 anisometropic amblyopic patients and 15 normal control subjects. The responses from the central 7.0° arc of the visual field were measured, and changes in latency and amplitude were compared between the amblyopic, fellow, and normal control eyes.

Results: There was a significant difference in the latency and amplitude of mfVEP between the amblyopic and fellow eyes. The responses in the central region of the visual field (rings 1 and 2) had a longer latency and smaller amplitude in the amblyopic eye. In contrast, there was no difference in mfVEP latency or amplitude between the fellow eye and normal control eyes.

Conclusion: These results suggest that mfVEP may be used as an alternative objective method for diagnosis and monitoring of anisometropic amblyopia.

Keywords: amblyopia, anisometropia, multifocal visual evoked potentials