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Local and Regional Anesthesia
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Methemoglobinemia due to topical pharyngeal anesthesia during endoscopic procedures
Review
(1407) Views (419) Full article downloads
Authors: Srikanth Vallurupalli
Published Date December 2010
Volume 2010:3 Pages 137 - 142
DOI: http://dx.doi.org/10.2147/LRA.S12227
Srikanth VallurupalliSouthern Illinois University College of Medicine, Springfield, IL, USA
Abstract: Acquired methemoglobinemia is a known complication of topical anesthesia during endoscopic procedures. Benzocaine has been implicated in a majority of cases and has been removed from some hospital formularies. However, a lot of uncertainty exists about the risk factors for this uncommon complication. This review attempts to summarize the current knowledge of this condition and describe known risk factors. Anesthetic and patient-specific risk factors are described along with some hypothetical procedure-related factors. Clinicians should identify patients who are at high risk and apply appropriate postprocedure screening. Prospective studies are needed to further our knowledge and improve patient safety.
Keywords: acquired methemoglobinemia, topical anesthetics, oxidative stress, endoscopy, transesophageal echocardiography (TEE)
Other articles by Dr Srikanth Vallurupalli
Clinical efficacy of beta1 selective adrenergic blockers in the treatment of neurocardiogenic syncope – a meta-analysis
Risk of acquired methemoglobinemia with different topical anesthetics during endoscopic procedures
Risk of acquired methemoglobinemia with different topical anesthetics during endoscopic procedures
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