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Lidocaine 5% patch for localized neuropathic pain: progress for the patient, a new approach for the physician

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Authors: Guy Hans, Dominique Robert, Johanna Verhulst, et al

Published Date March 2010 Volume 2010:2 Pages 65 - 70
DOI: http://dx.doi.org/10.2147/CPAA.S9795

Guy Hans1,2, Dominique Robert3, Johanna Verhulst2, Marcel Vercauteren1,2

1Department of Anesthesiology, 2Multidisciplinary Pain Center, 3Department of Intensive Care, Antwerp University Hospital, Edegem, Belgium

Abstract: Neuropathic pain (NeP) syndromes remain a difficult-to-treat medical entity. Despite a growing number of pharmacological and invasive analgesic therapies the results remain less than optimal because of insufficient analgesic efficacy and/or occurrence of pronounced side effects. Current guidelines propose the use of multimodal and balanced pharmacological therapies, focused on the underlying pathophysiological mechanisms (mechanistic approach). Lidocaine 5% patches are a new treatment option currently licensed for the treatment of postherpetic neuralgia. However, these patches can also be used for the treatment of different types of superficial NeP syndromes, such as diabetic polyneuropathy. Their therapeutic success, however, largely depends on the correct identification of appropriate patients and pain syndromes. This manuscript outlines the correct identification of patients and proper use of these patches in order to ensure as much as possible the therapeutic efficacy of this new treatment option.

Keywords: neuropathic pain, lidocaine, patch






 

Other articles by Professor Guy Hans

Altered sensitivity to mechanical stimulation during prolonged subcutaneous administration of endothelin-1 in rats
Outcome predictors for treatment success with 5% lidocaine medicated plaster in low back pain with neuropathic components and neuropathic pain after surgical and nonsurgical trauma
Transdermal buprenorphine – a critical appraisal of its role in pain management
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