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Transplant Research and Risk Management

Professor Yi

Professor Yi

Qing Yi, MD, PhD, is Chair and Staff, Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic.

 

Dr Yi is one of the leading investigators in the field of immune regulation and immunotherapy in multiple myeloma. He has been working on characterizing myeloma-specific T cells and their subsets, and examining their functions in relationship to myeloma tumor cells in both in vitro and in vivo experiments, and on identifying novel myeloma-associated antigens for immunotherapy. In addition, Dr Yi has been conducting clinical trials to evaluate the efficacy of immunizing patients with idiotype or dendritic cell-based vaccines. His research will continue focusing on the development of effective immunotherapy strategies to cure myeloma patients in combination with high-dose chemotherapy.

Recently, Dr Yi and his group discovered that anti-β2-microglublin antibodies could kill myeloma cells. His research team is thus examining whether these antibodies have therapeutic potentials to treat patients with myeloma. Furthermore, his recent studies demonstrate that C-reactive protein (CRP) protects myeloma cells from chemotherapy drug-induced apoptosis, and further work is under way to explore whether CRP can be targeted for myeloma therapy. Dr Yi’s research has been supported by US federal and foundation grants since 1998, and he has authored over 120 papers in the fields of myeloma research, immunotherapy of cancer, and tumor biology.

 


Honorary Editorial Board

Anthony Atala, Professor and Chief, Department of Urology, Wake Forest Institute for Regenerative Medicine, Medical Center Boulevard, Winston Salem, NC, USA

Bryan Becker, Professor, Department of Medicine, University of Wisconsin, Madison, WI, USA

James Blumenthal, Professor, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA

George W. Burke III, Professor, Department of Surgery, Chief, Kidney and Pancreas Transplant Program, University of Miami Miller School of Medicine, Miami, FL, USA

Elliot L. Chaikof, Professor, Department of Surgery, Emory University, Atlanta, GA, USA

Clark K. Colton, Professor, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge , MA

Robert E. Cone, Professor, Department of Immunology, University of Connecticut Health Center, Farmington, CT, USA

David K. C. Cooper, Professor, Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Michel Delahousse, Head, Nephrology and Kidney Transplant Unit, Hopital Foch, Suresnes, France

Wayne Hancock, Professor and Chief, Division of Transplantation Immunology, Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA

William G. Kerr, Immunology Program, H. Lee Moffitt Comprehensive Cancer Center and Research Institute, Tampa, FL, USA

Josh Levitsky, Medicine and Surgery, Division of Nephrology, Hypertension and Transplantation, Department of Medicine, University of Florida, Gainesville, FL, USA

Ram I. Mahato, Professor, Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN, USA

Mohammed Moghadasian, Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

Thalachallour Mohanakumar, Professor, Department of Surgery, Washington University School of Medicine, St Louis, MO, USA

Frederic I. Preffer, Department of Pathology, Massachusetts General Hospital, Boston, MA, USA

Camillo Ricordi, Professor, Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, FL, USA

Vinod K. Rustgi, Professor, Virginia Commonwealth University School of Medicine, Richmond, VA, USA

Michael G. Sarr, J. C. Masson Professor of Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA

Jesse D. Schold, Division of Nephrology, Hypertension and Transplantation, Department of Medicine, University of Florida, Gainesville, FL, USA

Ashok K. Shetty, Professor, Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, NC, USA

Paul Todd, Chief Scientist, Techshot, Inc., Greenville, IN, USA

Guido J. Tricot, Professor, Division of Hematology, Department of Internal Medicine, The University of Utah School of Medicine, Salt Lake City, UT, USA

Lori J. West, Professor of Pediatrics, Surgery and Immunology, Director of Heart Transplantation Research, University of Alberta, Edmonton, Alberta, Canada

John R. Wingard, Professor and Director, Bone Marrow Transplant Program, Division of Hematology/Oncology, University of Florida College of Medicine, Gainesville, FL, USA

George Yung-Hsing Wu, Professor and Director, Hepatology Section, Department of Medicine, University of Connecticut School of Medicine, Farmington, CT, USA

Xiaoming Yang, Professor, Department of Radiology, University of Washington School of Medicine, Seattle, WA, USA

Nicholas Zavazava, Professor and Director of Transplant Research, Division of Allergy/Immunology, Department of Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA