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Clinical Pharmacology: Advances and Applications

Dr Frankel

Dr Frankel

Editor-in-Chief:  Professor Arthur E. Frankel

Dr. Arthur Frankel is a Professor at the Department of Internal Medicine, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center.

Dr. Frankel earned his MD from Harvard Medical School and conducted his Medicine Internship at Yale University. Soon after completing his degree, Dr. Frankel began as a Research Scientist with the National Institute of Health and later completed his Medicine Residency and Oncology Fellowship at Stanford University. He is Board Certified in Internal Medicine, Medical Oncology and Hematology. Dr. Frankel is a member of the American Society of Clinical Oncology, American Society of Hematology and American Association of Cancer Research.

Dr. Frankel's main focus is combining the clinical practice of hematology/oncology with an investigative cancer drug development program to better move targeted cancer therapeutics into the clinical setting. He has participated in the development of targeted peptide toxins also called immunotoxins for melanoma, breast cancer, ovarian cancer, leukemia, lymphoma, chronic pain, prostate cancer, and thyroid cancer. He has performed phase I clinical trials for many of these agents. He has over 190 peer-reviewed articles, has edited three books, organized for international symposia and received grants from the American Cancer Society, the Leukemia and Lymphoma Society, NIH and the Van Andel Foundation.

Honorary Editorial Board

Rajesh Agarwal, Professor, Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Health Sciences Center, Denver, CO, USA

Steven A. Akman, Professor and Interim Chair, Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA

Mustafa al'Absi, Professor, Max and Mary LaDue Pickworth Chair, Director, Duluth Medical Research Institute (DMRI), University of Minnesota Medical School, Duluth, MN, USA

Alejandro C. Arroliga, Professor and Interim Chairman, Department of Medicine, Scott and White Hospital, Texas A&M Health Science Center, College of Medicine, Temple, TX, USA

Christopher Bachran, Laboratory of Bacterial Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

Henry H. Balfour, Jr, Professor, Laboratory Medicine, Pathology and Pediatrics, Medical Director, Division of Clinical Virology, University of Minnesota, Minneapolis, MN, USA

Julio C. Barredo, Director, Division of Pediatric Hematology-Oncology and Children’s Cancer Program, Toppel Family Professor of Pediatric Hematology-Oncology, University of Miami Miller School of Medicine, Miami, South Florida, USA

Kirby I. Bland, Fay Fletcher Kerner Professor and Chairman, Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

Mordecai P. Blaustein, Professor of Physiology and Medicine, Director, Maryland Center for Heart, Hypertension and Kidney Disease, Department of Physiology, University of Maryland School of Medicine, Baltimore, MD, USA

Jeffrey L. Blumer, Professor of Pediatrics and Pharmacology, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA

Kathleen T. Brady, Professor of Psychiatry, Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Medical University of South Carolina, Charleston, SC, USA

Bridget Brosnihan, Professor, Department of Physiology & Pharmacology, Department of Neuroscience, Wake Forest University School of Medicine, Winston-Salem, NC, USA

Kim L. R. Brouwer, William R. Kenan, Jr., Distinguished Professor and Chair, Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA

Edmund V. Capparelli, Clinical Professor and Director, Pediatric Pharmacology Research Unit, University of California, San Diego, CA, USA

John D. Catravas, Regents' Professor of Pharmacology, Director, Vascular Biology Center, Senior Associate Dean for Basic Research, Medical College of Georgia, Augusta, GA, USA

William C. Cho, Ph.D., Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong

James M. Cook, University Distinguished Professor, Chemistry Department, University of Wisconsin-Milwaukee, Milwaukee, WI, USA

Steven M. Dubinett, Professor of Medicine and Pathology, Chief, Division of Pulmonary and Critical Care Medicine, Director, UCLA Lung Cancer Research Program, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

Nicholas S. Duesbery, Deputy Director for Research Operations and Senior Scientific Investigator of the Laboratory of Cancer and Developmental Cell Biology, Van Andel Institute, Grand Rapids, MI, USA

Nae J. Dun, Professor and Chairman, Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA

M. Elizabeth Fini, Professor of Cell and Neurobiology, Vice Dean for Research Advancement, Interim Director, Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

Joseph A. Fontana, Professor of Internal Medicine and Oncology, Karmanos Cancer Institite and Wayne State University, Chief of Hematology and Medical Oncology, John D. Dingell VA Medical Center, Detroit, Michigan, USA

William R. Freeman, Professor of Ophthalmology, Director Joan and Irwin Jacobs Retina Center, School of Medicine, University of California San Diego, La Jolla, USA

Laura J. Frishman, Moores Professor, Associate Dean, College of Optometry, University of Houston, Calhoun, Houston, TX, USA

Hendrik Fuchs, Privatdozent of Biochemistry and Pathobiochemistry, Head of the Laboratory of Molecular Tumor Therapy, Central Department of Laboratory Medicine and Pathobiochemistry, Charité - Universitätsmedizin Berlin, Germany

Henry Fung, Coleman Foundation Professor of Blood and Marrow Transplantation, Director, Section of Stem Cell Transplantation, Professor of Medicine, Rush University School of Medicine, Chicago, IL, USA

Ramesh Ganju, Scott Endowed Professor of Pathology, Vice-Chair Experimental Pathology, Ohio State University, Columbus, OH, USA

Juri G. Gelovani, Professor and Chairman, Department of Experimental Diagnostic Imaging, Director, Center for Advanced Biomedical Imaging Research, UT MD Anderson Cancer Center, Houston, TX, USA

Francis J. Giles, Professor and Chief, Division of Hematology and Medical Oncology, University of TX Health Science Center, San Antonio, TX, USA

Daniel Gillet, Chief of the Laboratory of Molecular Toxinology and Biotechnology, Section of Molecular Engineering of Proteins, Institute of Biology and Technologies of Saclay, Life Sciences Division, CEA, France

Leo Gordon, Professor, Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

Sanjeev Gupta, Professor of Medicine and Pathology, Albert Einstein College of Medicine, Bronx, NY, USA

Donna Hogge, Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Aminah Jatoi, Professor, Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA

Naijie Jing, Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA

Pedro A. Jose, Professor of Pediatrics, Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Director, Center for Molecular Physiology Research, Children's National Medical Center, Washington, DC, USA

Paul L. Kaufman, Peter A. Duehr Professor and Chairman, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, WI, USA

Robert J. Kreitman, Chief, Clinical Immunotherapy Section, Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

Macus Tien Kuo, Felix Haas Professor, Department of Molecular Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

Terry C. Lairmore, Professor of Surgery, Director, Division of Surgical Oncology, Vice Chairman for Research, Scott and White Memorial Hospital and Clinic, Texas A&M University System Health Sciences Center, College of Medicine, Temple, TX, USA

Douglas A. Lappi, President and Chief Scientific Officer, Advanced Targeting Systems, San Diego, CA, USA

Julio Licinio, Miller Professor, Associate Dean for Project Development (Translational Sciences), Professor of Medicine and Endocrinology, University of Miami Miller School of Medicine, Miami, FL, USA

Charles Q. Liu, Principal Scientist, Bioanalysis US Pharmacodynamics, Drug Discovery Research, Astellas Pharma Global Development, Skokie, IL, USA

Edythe D. London, Katherine K. and Thomas P. Pike Professor of Addiction Studies, Professor of Psychiatry, and Professor of Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, USA

Craig Malbon, Leading Professor and Director, DMDRC, State University of New York, Stony Brook, NY, USA

Kafait U. Malik, Professor of Pharmacology and Vice Chair, College of Medicine, University of Tennessee, Center for Health Sciences, Memphis, TN, USA

Craig J. McClain, Professor of Medicine, Department of Medicine, Division of Gastroenterology/Hepatology, University of Louisville School of Medicine and Louisville VAMC, Louisville, KY, USA

Lucio Miele, Ergon Professor of Medicine and Pharmacology, Director, University of Mississippi Cancer Institute, University of Mississippi Medical Center Cancer Institute, Jackson, MS, USA

Arlynn F. Mulne, Chief, Pediatric Hematology/Oncology, The Children's Hospital at Scott and White, Temple, TX, USA

David Neville, Section on Biophysical Chemistry, Laboratory of Molecular Biology, NIMH, Bethesda, MD, USA

Hui-Lin Pan, Helen T. Hawkins Distinguished Professor and Deputy Division Head for Research, Department of Anesthesiology and Perioperative Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

Gavril W. Pasternak, Anne Burnett Tandy Chair in Neurology,Memorial Sloan-Kettering Cancer Center, Professor of Neurology and Neuroscience, Pharmacology and Psychiatry, Weill College of Medicine of Cornell University, Manhattan, New York City, NY, USA

Steven Piantadosi, Director, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Bruce G. Pollock, Sandra A. Rotman Chair in Neuropsychiatry, Professor and Head, Division of Geriatric Psychiatry, Vice President Research, Centre for Addiction and Mental Health, University of Toronto, Faculty of Medicine, Toronto, Canada

David G. Poplack, Elise C. Young Professor of Pediatric Oncology, Director, Texas Children's Cancer Center, Head, Hematology-Oncology Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA

Katya Ravid, Professor of Biochemistry and Medicine, Director, Evans Center for Interdisciplinary Biomedical Research, Boston University School of Medicine, Boston, MA, USA

Gregory H. Reaman, Adjunct Professor of Oncology and Pediatrics, Georgetown University School of Medicine, Executive Director for Scientific and Medical Affairs, National Childhood Cancer Foundation, Bethesda, Maryland, USA

Eva E. Redei, David Lawrence Stein Professor, Department of Psychiatry and Behavioral Sciences, Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

Scot C. Remick, Director and Professor of Medicine, The Laurence and Jean DeLynn Chair of Oncology, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, USA

Stephen H. Safe, Distinguished Professor, Department of Veterinary Physiology & Pharmacology, Director, Center for Environmental and Genetic Medicine, Institute of Biosciences and Technology, Texas A&M University and Health Science Center, College Station, TX, USA

Alan C. Sartorelli, Alfred Gilman Professor of Pharmacology, Yale University School of Medicine, New Haven, CT, USA

J. Philip Saul, Professor of Pediatrics, Cell Biology and Anatomy, Chief, Pediatric Cardiology, Director, The Childrend's Heart Program of South Carolina, Medical University of South Carolina, Charleston, SC, USA

David A. Scheinberg, Professor of Medicine and Pharmacology, Weill-Cornell University Medicial College, Vincent Astor Chair and Chairman, Molecular Pharmacology and Chemistry Program, Sloan-Kettering Institute, New York, NY, USA

Alan D. Stiles, Brewer Distinguished Professor and Chair, Department of Pediatrics, Physician in Chief, NC Children's Hospital, Chapel Hill, NC, USA

Giles Tamagnan, Director, Laboratory Research and Development, Molecular Neurolmaging LLC and Institute for Neurodegenerative Disorders, Associate Professor, Yale School of Medicine, New Haven, CT, USA

Daniel A. Vallera, Professor of Therapeutic Radiology - Radiation Oncology, Lion Scholar and Director, Section on Molecular Cancer Therapeutics, University of Minnesota Cancer Center, Minnesota, USA

Koen van Besien, Professor of Medicine and Pediatrics, Director of Stem Cell Transplantation and Lymphoma, University of Chicago, Chicago, Illinois, USA

John N. van den Anker, Professor of Pediatrics, Pharmacology and Physiology, George Washington University, Executive Director of Pediatric Pharmacology Research Unit, Director of Pediatric Clinical Pharmacology, Children's National Medical Centre, Washington, DC, USA

Yu-Jui Yvonne Wan, Professor of Pharmacology, Department of Pathology and Laboratory Medicine, UC Davis Medical Center, Ca, USA

Donna Wang, Distinguished Professor, Chief, Division of Nanomedicine and Molecular Intervention, Michigan State University, East Lansing, Michigan, USA

Mariusz Wasik, Professor, Director of Experimental Hematology, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

David J. Waxman, Professor of Cell and Molecular Biology and Professor of Medicine, Boston University, Boston, Massachusetts, USA

Robert N. Weinreb, Distinguished Professor of Ophthalmology, Director, Hamilton Glaucoma Center, University of California, San Diego, USA

William G. North, Professor of Physiology, Dartmouth Medical School, Hanover, NH, USA

Katherine Wisner, Professor of Psychiatry, Obstetrics, Gynecology and Reproductive Sciences, Epidemiology and Women's Studies, Director, Women's Behavioral HealthCARE, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, USA

Ma-Li Wong, Miller Professor, Vice Chair for Translational Research, Director, Center on Pharmacogenomics, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA

Jung Hee Woo, Associate Director, Cancer Research Institute, Department of Internal Medicine, Scott and White Memorial Hospital, College of Medicine, Texas A&M University System Health Science Center, Temple, TX, USA