skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8852

Intranasal fentanyl for pain control: current status with a focus on patient considerations

Review

(1966) Views  (429) Full article downloads

Authors: Eric Prommer, Lisa Thompson

Published Date March 2011 Volume 2011:5 Pages 157 - 164
DOI: http://dx.doi.org/10.2147/PPA.S7665

Eric Prommer, Lisa Thompson
Division of Hematology/Oncology, Mayo Clinic College of Medicine, Mayo Clinic Hospital, Scottsdale, AZ, USA

Abstract: Of several newer delivery systems under development and investigation for the administration of opioids, the intranasal route has received a substantial amount of attention. Intranasal administration is a convenient form of delivery that is applicable to several opioids. It has the potential for self-administration, combined with a rapid onset of action, allowing for patient-controlled analgesia. In clinical practice, intranasal administration has been found to be a reliable drug delivery method that is familiar to patients. Intranasal opioids have proven to be useful in both in-hospital and out-of-hospital pain management settings. Fentanyl, a highly lipophilic step 3 opioid, has been evaluated for intranasal administration. The purpose of this review is to examine the role of the nasal route of opioid administration and examine the evidence base for the use of fentanyl intranasally.

Keywords: fentanyl, intranasal, pain, breakthrough pain




 

Other articles by Dr Eric Prommer



Readers of this article also read:

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors
"Globalized public health.” A transdisciplinary comprehensive framework for analyzing contemporary globalization’s influences on the field of public health
Trans fatty acids and coronary artery disease
Health literacy and health seeking behavior among older men in a middle-income nation
Clinical and economic considerations of antiobesity treatment: a review of orlistat
Morphological and functional MDCT: problem-solving tool and surrogate biomarker for hepatic disease clinical care and drug discovery in the era of personalized medicine
Molecular mechanisms of hyperglycemia and cardiovascular-related events in critically ill patients: rationale for the clinical benefits of insulin therapy
Optimal management of urinary tract infections in older people
Primary care for diabetes mellitus: perspective from older patients
Impact of pharmacist interventions on patients' adherence to antidepressants and patient-reported outcomes: a systematic review