Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

Original Research

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Author:

IP Theocharis

Published Date February 2010 Volume 2010:4 Pages 73 - 76

DOI: http://dx.doi.org/10.2147/OPTH.S8599

IP Theocharis

Ophthalmology Department, Iaso General Hospital, Athens, Greece

Purpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD).
Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;
Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded.
Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.
Keywords: fibrinogen, retinal detachment, pathogenesis