Epidemiology and treatment of post-stroke depression

Review

(2710) Views  (773) Full article downloads

Author: Stefano Paolucci

Published Date March 2008 Volume 2008:4(1) Pages 145 - 154

DOI: http://dx.doi.org/10.2147/NDT.S2017

Stefano Paolucci

Fondazione Santa Lucia – I.R.C.C.S, Rome, Italy

Abstract: Mood depression is a common and serious complication after stroke. According to epidemiological studies, nearly 30% of stroke patients develop depression, either in the early or in the late stages after stroke. Although depression may affect functional recovery and quality of life after stroke, such condition is often ignored. In fact, only a minority of patients is diagnosed and even fewer are treated in the common clinical practice. Moreover, the real benefits of antidepressant (AD) therapy in post-stroke depression have not been fully clarified. In fact, controlled studies on the effectiveness of ADs in post stroke depression (PSD) are relatively few. Today, data available suggest that ADs may be generally effective in improving mood, but guidelines for the optimal treatment and its length are still lacking.

Keywords: depression, stroke, antidepressant