-
Journal of Blood Medicine
-
About Dovepress
Open access peer-reviewed scientific and medical journals.
-
Open Access
Dove Medical Press is now a member of the Open Access Initiative
-
An Author's Guide
A guide to help authors get their paper published.
-
Advocacy
Support Open Access and Dove Press
-
Reprints
Promotional Article Monitoring - further details
-
Favored Author Program
Real benefits for authors, including fast-track processing of papers.
Efficacy of dasatinib for the treatment of intractable chronic myeloid leukemia
Review
(2340) Views (710) Full article downloads
Authors: Lisa M Lima, Martha Arellano, Stacie Holloway, et al
Published Date September 2010
Volume 2010:1 Pages 221 - 225
DOI: http://dx.doi.org/10.2147/JBM.S7158
Lisa M Lima, Martha Arellano, Stacie Holloway, Marian Shepard, Stephanie McMillan, Hanna Jean KhouryDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA
Abstract: Dasatinib (DAS) is a well tolerated oral dual SRC inhibitor with remarkable activity against all phases of imatinib-resistant chronic myeloid leukemia (CML). This paper focuses on the activity of DAS in intractable CML, and reviews outcomes of patients enrolled on DAS clinical trials. Safety and tolerability as well as practical tips for management of side-effects, and drug interactions are included.
Keywords: dasatinib, resistant CML, outcomes
Readers of this article also read:
Potential renovascular hypertension, space missions, and the role of magnesium
Critical appraisal of the role of glucosamine and chondroitin in the management of osteoarthritis of the knee
Ego mechanisms of defense are associated with patients’ preference of treatment modality independent of psychological distress in end-stage renal disease
Can a gentamicin-specific chart reduce neonatal medication errors?
Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology
Nephroprotective action of glycosaminoglycans: why the pharmacological properties of sulodexide might be reconsidered
Dashboards in neonatology
Deep vein thrombosis: a clinical review
Comparison of two treatments for coxarthrosis: local hyperthermia versus radio electric asymmetrical brain stimulation
- Testimonials
"You do a tremendous job!!" Ruben Restrepo, The University of Texas Health Science Center at San Antonio
- Use of sulodexide in patients with peripheral vascular disease
- Treatment of hemophilia: a review of current advances and ongoing issues
- ABO and rhesus blood group distribution in Kurds
- Deep vein thrombosis: a clinical review




