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Diffuse iris melanoma: Report of a case with review of the literature

Authors Simon E Skalicky, Michael Giblin, R Max Conway

Published 15 December 2007 Volume 2007:1(3) Pages 339—342



Simon E Skalicky, Michael Giblin, R Max Conway

Save Sight Institute, Sydney Eye Hospital, 8 Macquarie Street, Sydney, NSW, Australia; University of Sydney, Sydney, NSW, Australia

Abstract: Diffuse iris melanoma is an uncommon variant of anterior uveal melanoma. It is characterized by heterochromia and unilateral glaucoma secondary to angle invasion, and can be difficult to diagnose. We present a patient who had been managed for left-sided raised intraocular pressure with latanoprost eye drops for 12-months and pigmentary changes were subsequently noted. On referral to the Ocular Oncology Unit, Sydney, iris melanoma was suspected and confirmed on iridectomy, and the eye was eventually enucleated.

Keywords: iris, diffuse melanoma, glaucoma, latanoprost, cytogenetics