Back to Browse Journals » Substance Abuse and Rehabilitation » Volume 2 » Issue 1

Differences in onset and abuse/dependence episodes between prescription opioids and heroin: results from the National Epidemiologic Survey on Alcohol and Related Conditions

Authors Wu LT, Woody GE, Yang C, Mannelli P, Blazer DG

Published Date May 2011 Volume 2011:2(1) Pages 77—88

DOI http://dx.doi.org/10.2147/SAR.S18969

Published 3 May 2011

Li-Tzy Wu1, George E Woody2, Chongming Yang3, Paolo Mannelli1, Dan G Blazer1
1Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, NC, USA; 2Department of Psychiatry, University of Pennsylvania School of Medicine, University of Pennsylvania and Treatment Research Institute, Philadelphia, PA, USA; 3Social Science Research Institute, Duke University, Durham, NC, USA

Objectives: To examine patterns of onset and abuse/dependence episodes of prescription opioid (PO) and heroin use disorders in a national sample of adults, and to explore differences by gender and substance abuse treatment status.
Methods: Analyses of data from the 2001–2002 National Epidemiologic Survey on Alcohol and Related Conditions (N = 43,093).
Results: Of all respondents, 5% (n = 1815) reported a history of nonmedical PO use (NMPOU) and 0.3% (n = 150) a history of heroin use. Abuse was more prevalent than dependence among NMPOUs (PO abuse, 29%; dependence, 7%) and heroin users (heroin abuse, 63%; dependence, 28%). Heroin users reported a short mean interval from first use to onset of abuse (1.5 years) or dependence (2.0 years), and a lengthy mean duration for the longest episode of abuse (66 months) or dependence (59 months); the corresponding mean estimates for PO abuse and dependence among NMPOUs were 2.6 and 2.9 years, respectively, and 31 and 49 months, respectively. The mean number of years from first use to remission from the most recent episode was 6.9 years for PO abuse and 8.1 years for dependence; the mean number of years from first heroin use to remission from the most recent episode was 8.5 years for heroin abuse and 9.7 years for dependence. Most individuals with PO or heroin use disorders were remitted from the most recent episode. Treated individuals, whether their problem was heroin or POs, tended to have a longer mean duration of an episode than untreated individuals.
Conclusion: Periodic remissions from opioid or heroin abuse or dependence episodes occur commonly but take a long time. Timely and effective use of treatment services are needed to mitigate the many adverse consequences from opioid/heroin abuse and dependence.

Keywords: comorbidity, heroin use disorders, natural recovery, opioid use disorders, prescription opioid abuse, self-change

Download Article [PDF] View Full Text [HTML] 

Creative Commons License This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution - Non Commercial (unported, v3.0) License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be found at: http://www.dovepress.com/permissions.php

Readers of this article also read:

Secondhand smoke exposure among young adults in a developing country – a Jordanian case

Haddad L, Abu Baker N, EL-Shahawy O, Al-Ali N, Shudayfat T

Substance Abuse and Rehabilitation 2013, 4:45-53

Published Date: 24 April 2013

The effect of cannabis use on memory function: an update

Schoeler T, Bhattacharyya S

Substance Abuse and Rehabilitation 2013, 4:11-27

Published Date: 23 January 2013

Social capital and cigarette smoking among Latinos in the United States

Li S , Horner P, Delva J

Substance Abuse and Rehabilitation 2012, 3:83-92

Published Date: 3 May 2012

Improving drug abuse treatment delivery through adoption of harmonized electronic health record systems

Ghitza UE, Sparenborg S, Tai B

Substance Abuse and Rehabilitation 2011, 2:125-131

Published Date: 18 July 2011