skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8847

Computer simulation of a novel pharmaceutical silicon nanocarrier

Other

(2248) Views  (856) Full article downloads

Authors: Saeed Soltani, Soroush Sardar, Sima Azadi Soror

Published Date November 2010 Volume 2010:3 Pages 149 - 157
DOI: http://dx.doi.org/10.2147/NSA.S8378

Saeed Soltani, Soroush Sardari, Sima Azadi Soror
Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran

Abstract: We show the potential of the nanosilicon structure of the frustules of a typical diatom, Cymatopleura sp., as a new vehicle for drugs. The basic diatom nanostructure is a lattice of SiO2, and computerized methods in a dock project have identified the most likely and the best drug types to load into such a structure.

Keywords: diatom, docking, artificial neural network, simulation, computerized methods






Readers of this article also read:

Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors
Refinement of rigid-body protein–protein docking using backbone and side-chain minimization with a coarse-grained model
Erratum
Biosensors: the new wave in cancer diagnosis
Fullerene fine particles adhere to pollen grains and affect their autofluorescence and germination
The relationship between deliberate self-harm behavior, body dissatisfaction, and suicide in adolescents: current concepts
Zinc oxide nanoparticles as selective killers of proliferating cells
An in silico approach to primaquine binding to Trp756 in the external vestibule of sodium channel Nav 1.4
Cumulative clinical experience from over a decade of use of levofloxacin in community-acquired pneumonia: critical appraisal and role in therapy
Helicobacter pylori infection and primary open-angle glaucoma: is there a connection?
  • Testimonials

    "... I was impressed at the rapidity of publication from submission to final acceptance." Dr Edwin Thrower, PhD, Yale University