skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8847

Clinicoradiological features of recurrent ischemic stroke: healthcare for poststroke patients

Original Research

(1567) Views  (379) Full article downloads

Authors: Takehisa Hirayama, Yoshikazu Nakamura, Yasuhiro Yoshii, et al

Published Date July 2010 Volume 2010:3 Pages 97 - 101
DOI: http://dx.doi.org/10.2147/JMDH.S11033

Takehisa Hirayama, Yoshikazu Nakamura, Yasuhiro Yoshii, Ken Ikeda

Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan

Objective: Little is known about recurrent risk profile of brain infarct (BI) in Japan. The study aimed to clarify clinicoradiological features of recurrent BI patients.

Methods: 374 consecutive BI patients (231 men and 143 women) were admitted to our ­department between 2007 and 2008. Recurrent BI was defined as a prior history of BI. ­Cardiovascular disease (CVD) risk profile, stroke mechanism subtypes and Bamford subtypes were compared between the first BI and the recurrent BI group. CVD risk factors, stroke subtypes of the first BI and preventative medication were analyzed in recurrent BI patients.

Results: Recurrent BI existed in 72 patients (40 men and 32 women). Age of the recurrent BI group was significantly older than the first BI group (P < 0.01). In comparison to the first BI group, the recurrent BI group had a high frequency of hypertension (P < 0.01) and CVD comorbidity (P < 0.05). Recurrent rates were increased significantly in cardioembolic patients as compared to the first BI patients (P < 0.05). Bamford BI subtypes did not differ between both groups. Mean recurrent interval (SD) was 3.1 (2.3) years. Approximately half the patients experienced recurrent BI less than 2 years after the first BI. Antiplatelet agents were used in 33 patients and warfarin was used in 12 patients as preventative medication. The remaining 27 patients had no prevention therapy by self-cessation. Nine warfarin users were controlled poorly. There were no significant correlations between the first and recurrent Bamford subtypes in recurrent BI patients.

Conclusions: The present study indicated that the recurrent frequency of BI was 19.3%. Causative profile of recurrent BI suggested elderly age (≥65 years), hypertension, prior history of CVD, cardioembolism, 2 years poststroke, insufficient treatment of warfarin and self-cessation of preventative medication. Thus, physicians should pay more attention to these aspects for prophylaxis of recurrent BI in poststroke patients.

Keywords: brain infarct, recurrence, cardiovascular disease risk profile, secondary prevention





 

Other articles by Professor Ken Ikeda



Readers of this article also read:

Is gene activity in plant cells affected by UMTS-irradiation? A whole genome approach
Wine consumers’ environmental knowledge and attitudes: Influence on willingness to purchase
A controlled study of the effect of a mindfulness-based stress reduction technique in women with multiple chemical sensitivity, chronic fatigue syndrome, and fibromyalgia
Periosteoplasty for covering gingival recessions: Clinical results
Nurse stress at two different organizational settings in Alexandria
Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors
A comparative study of DNA damage in patients suffering from diabetes and thyroid dysfunction and complications
Wine fraud
Using systematically observed clinical encounters (SOCEs) to assess medical students’ skills in clinical settings
Improvement of adenoviral vector-mediated gene transfer to airway epithelia by folate-modified anionic liposomes
  • Testimonials

    "You do a tremendous job!!" Ruben Restrepo, The University of Texas Health Science Center at San Antonio