Clear cell eccrine carcinoma with comedonecrosis in neck region: a  rare case report and review of literature

Alka H Hande, Archana M Sonone, Minal S Chaudhary

Department of Oral and Maxillofacial Pathology, Sharad Pawar Dental College, Sawangi (Meghe), Wardha, India

Abstract: Adnexal carcinomas of the skin are rare; they derive from structures such as sweat glands, sebaceous glands, and hair follicles. Adnexal tumors represent 1%–2% of skin cancers. Carcinomas of the eccrine sweat gland represent a rare group of tumors with potential for local destruction and metastasis. Clear cell changes are a prominent feature in a wide variety of squamous and adnexal carcinomas. Pure clear cell carcinomas of the skin are exceptionally rare. Eccrine clear cell carcinoma is most commonly seen in the scalp region. We represent a rare case report of clear cell eccrine carcinoma with comedonecrosis in the neck region which is an unusual location for this type of tumor.

Keywords: adnexal carcinomas, carcinomas of the eccrine sweat gland, clear cell eccrine carcinoma with comedonecrosis