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3655

Biologics: Targets & Therapy

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Editor in Chief Professor Doris Mangiaracina Benbrook

1177-5475

New advances in the treatment of adult chronic immune thrombocytopenic purpura: role of thrombopoietin receptor-stimulating agents
Ara Metjian, Charles S Abrams

Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug  Effectiveness Review Project
Kylie Thaler, Divya V Chandiramani, Richard A Hansen, et al

Targeted therapy in melanoma
Hussein Tawbi, Neelima Nimmagadda

Local cytokines and clinical symptoms in children with allergic rhinitis after different treatments
Gesmar RS Segundo, Fabíola A Gomes, Karla P Fernandes, et al

A systematic review of new advances in the management of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): focus on galsulfase
Regina P El Dib, Gregory M Pastores

Biological targets in the treatment of rheumatoid arthritis: a comprehensive review of current and in-development biological disease modifying anti-rheumatic drugs
Manil Kukar, Olga Petryna, Petros Efthimiou

Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies
Laith Altaweel, Daniel Sweeney, Xizhong Cui, et al

Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
Bryan A Faller, Barbara Burtness

Current use and potential role of bevacizumab in the treatment of gastrointestinal cancers
Jia Li, Muhammad Wasif Saif

Review of the safety and efficacy of imiglucerase treatment of Gaucher disease
Deborah Elstein, Ari Zimran

Safety and efficacy of pegylated liposomal doxorubicin in HIV-associated Kaposi’s sarcoma
Francesca Cainelli, Alfredo Vallone

Finding a new drug and vaccine for emerging swine flu: What is the concept?
Viroj Wiwanitkit

Review of interferon beta-1b in the treatment of early and relapsing multiple sclerosis
Damiano Paolicelli, Vita Direnzo, Maria Trojano

First-line treatment of acute lymphoblastic leukemia with pegasparaginase
Riccardo Masetti, Andrea Pession

Lutropin alpha, recombinant human luteinizing hormone, for the stimulation of follicular development in profoundly LH-deficient hypogonadotropic hypogonadal women: a review

Bernd Th Krause, Ralf Ohlinger, Annette Haase



Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID
Claire Booth, H Bobby Gaspar

Anti-interleukin-2 receptor antibodies—basiliximab and daclizumab—for the prevention of acute rejection in renal transplantation
Junichiro Sageshima, Gaetano Ciancio, Linda Chen, George W Burke III

HER2 breast cancer therapies: a review
Conleth G Murphy, Shanu Modi

Targeted treatment of psoriasis with adalimumab: a critical appraisal based on a systematic review of the literature
Jochen Schmitt, Gottfried Wozel

The old and new therapeutic approaches to the treatment of giardiasis: Where are we?
Haendel GNO Busatti, Joseph FG Santos, Maria A Gomes

Early stage and long term treatment of multiple sclerosis with interferon-β
Angela Applebee, Hillel Panitch

Potentials and limitations of microorganisms as renal failure biotherapeutics
Poonam Jain, Sapna Shah, Razek Coussa, Satya Prakash

Methods, potentials, and limitations of gene delivery to regenerate central nervous system cells
Arvind Kumar, Tryambak D Singh, Santosh K Singh, Satya Prakash

B cell reductive therapy with rituximab in the treatment of rheumatoid arthritis
Joseph M Tuscano, Jacob Sands

EGFR targeted therapy in non-small cell lung cancer: potential role of cetuximab
Chad A Reade, Apar Kishor Ganti

Dasatinib in the treatment of imatinib refractory chronic myeloid leukemia
Radhakrishnan Ramchandren, Charles A Schiffer

Infliximab in the treatment of rheumatoid arthritis
A Perdriger

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency
Irina Petrache, Joud Hajjar, Michael Campos

Long-term pegylated interferon-α and its potential in the treatment of melanoma
Reinhard Dummer, Joanna Mangana

Ustekinumab in the therapy of chronic plaque psoriasis
Jenna L O’Neill, Robert E Kalb

Treatment of immune thrombocytopenic purpura: focus on eltrombopag
Lawrence Rice

Management of chronic hepatitis C treatment failures: role of consensus interferon
Stevan A Gonzalez, Emmet B Keeffe

Challenges in the management of juvenile idiopathic arthritis with etanercept
Clare E Pain, Liza J McCann

Palifermin for management of treatment-induced oral mucositis in cancer patients
Andrei Barasch, Joel Epstein, Ken Tilashalski

Antihemophilic factor (recombinant) plasma/albumin-free method for the management and prevention of bleeding episodes in patients with hemophilia A
Steven Pipe

Biologic targeting in the treatment of inflammatory bowel diseases
Matteo Bosani, Sandro Ardizzone, Gabriele Bianchi Porro

Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency
Caitriona McLean, Catherine M Greene, Noel G McElvaney

Basiliximab induction therapy in kidney transplantation: Benefits for long term allograft function after 10 years?
Martina Koch, Thomas Becker, Rainer Lueck, Michael Neipp, Juergen Klempnauer, Bjoern Nashan

Anti-RhD immunoglobulin in the treatment of immune thrombocytopenia
Eric Cheung, Howard A Liebman

Maintenance treatment with infliximab for the management of Crohn’s disease in adults
Renato Caviglia, Ivo Boškoski, Michele Cicala

Current available therapies and future directions in the treatment of malignant gliomas
Annick Desjardins, David A Reardon, James J Vredenburgh

Effectiveness of cytopenia prophylaxis for different filgrastim and pegfilgrastim schedules in a chemotherapy mouse model
Markus Scholz, Manuela Ackermann, Frank Emmrich, Markus Loeffler, Manja Kamprad

Adjuvant treatment with thyrotropin alpha for remnant ablation in thyroid cancer
Bernadette Biondi, Melania Pulcrano, Loredana Pagano, Gaetano Lombardi

Botulinum toxin type A in the treatment of patients with cervical dystonia
Allison Brashear

Front line treatment of elderly multiple myeloma in the era of novel agents
Marie-Dominique Venon, Aldo M Roccaro, Julie Gay, Anne-Sophie Moreau, Remy Dulery, et al

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