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3678

Biologics: Targets & Therapy

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Editor in Chief Professor Doris Mangiaracina Benbrook

1177-5475

Anticomplement therapy
Prathit A Kulkarni, Vahid Afshar-Kharghan

Abatacept in difficult-to-treat juvenile idiopathic arthritis
Jasmin B Kuemmerle-Deschner, SM Benseler

Therapeutic vaccines for malignant brain tumors
Michael P Gustafson, Keith L Knutson, Allan B Dietz

Denileukin diftitox for the treatment of cutaneous T-cell lymphoma
David Kaminetzky, Kenneth B Hymes

Bevacizumab in the treatment of HER2-negative breast cancer
Vito Lorusso

Association of pro/anti-inflammatory cytokine gene variants in renal transplant patients with allograft outcome and cyclosporine immunosuppressant levels
Parmeet Kaur Manchanda, Anant Kumar, Raj K Sharma, Himanshu Goel, Rama Devi Mittal

Effect of extended-release niacin on hormone-sensitive lipase and lipoprotein lipase in patients with HIV-associated lipodystrophy syndrome
Dominic C Chow, Anne Tasaki, Jill Ono, Bruce Shiramizu, Scott A Souza

Sorafenib for the treatment of unresectable hepatocellular carcinoma
Junji Furuse

Safety and efficacy of enzyme replacement therapy in the nephropathy of Fabry disease
Fernando C Fervenza, Roser Torra, David G Warnock

Efalizumab-induced severe thrombocytopenia can be resolved
Francesca Prignano, F Zanieri, S Mokhtarzadeh, T Lotti

Rituximab therapy in Greek patients with rheumatoid arthritis
Aristotelis P Tsiakalos, Nestor K Avgoustidis, Haralampos M Moutsopoulos

Novel microtubule-targeting agents – the epothilones
Kit L Cheng, Thomas Bradley, Daniel R Budman

Etiology of hypercoagulable state in women with recurrent fetal loss without other causes of miscarriage from Southern Italy: new clinical target for antithrombotic therapy
Maristella D’Uva, Pierpaolo Di Micco, Ida Strina, Antonio Ranieri, Carlo Alviggi, et al

Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap)
Leigh D Church, Sinisa Savic, Michael F McDermott

Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies
Steven J Greco, Pranela Rameshwar

Small molecule tyrosine kinase inhibitors in pancreatic cancer
Sachin Gupta, Bassel F El-Rayes

Review of recombinant human deoxyribonuclease (rhDNase) in the management of patients with cystic fibrosis
Tacjana Pressler

Review of consensus interferon in the treatment of chronic hepatitis C
Th Witthöft

Rituximab in the treatment of non-Hodgkin’s lymphoma
Beate Hauptrock, Georg Hess

The insulin-like growth factor system and its receptors: A potential novel anticancer target
Colin R. Lindsay, T R Jeffry Evans

Adalimumab for the treatment of Crohn’s disease
Andrea Cassinotti, Sandro Ardizzone, Gabriele Bianchi Porro

Prevention of bone mineral density loss in patients with rheumatoid arthritis treated with anti-TNFα therapy
Hubert Marotte, Pierre Miossec

α-L-iduronidase therapy for mucopolysaccharidosis type I
Jakub Tolar, Paul J Orchard

Use of a decoy peptide to purify p21 activated kinase-1 in cardiac muscle and identification of ceramide-related activation
Yunbo Ke, R John Solaro

Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines
Faten Merhi, Jacques Auger, Francine Rendu, Brigitte Bauvois

Biological drugs targeting the immune response in the therapy of psoriasis
Saveria Pastore, Emanuela Gubinelli, Luca Leoni, Desanka Raskovic, Liudmila Korkina

Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation
Raj Kumar, William J Calhoun

Ranpirnase and its potential for the treatment of unresectable malignant mesothelioma
Camillo Porta, Chiara Paglino, Luciano Mutti

Denosumab: an investigational drug for the management of postmenopausal osteoporosis
E Michael Lewiecki

Treatment of short stature and growth hormone deficiency in children with somatotropin (rDNA origin)
Dana S Hardin

Clinical use of topical thrombin as a surgical hemostat
Wesley K Lew, Fred A Weaver

The target of arachidonic acid pathway is a new anticancer strategy for human prostate cancer
Masahide Matsuyama, Rikio Yoshimura

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