skip to content
Dovepress - Open Access to Scientific and Medical Research
View our mobile site

8129

Angiotensin II receptor blockers in the prevention of complications from atrial fibrillation

Review

(2508) Views  (925) Full article downloads

Authors: Gerald V Naccarelli, Frank Peacock

Published Date September 2009 Volume 2009:5 Pages 783 - 791
DOI: http://dx.doi.org/10.2147/VHRM.S7616

Gerald V Naccarelli,1 Frank Peacock2

1Penn State Heart and Vascular institute, Hershey, Pennsylvania, USA; 2Cleveland Clinic, Cleveland, Ohio, USA

Abstract: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia and is associated with an increased risk of cardiovascular morbidity and mortality, especially due to ischemic stroke. The occurrence of AF leads to atrial electrical and structural remodeling. The renin-angiotensin system appears to play a role in the development of atrial arrhythmias by its involvement in both of these processes. Large-scale hypertension trials and heart failure trials have indicated the potential value of angiotensin II receptor blockers in the treatment of AF.

Keywords: angiotensin II receptor blockers, atrial fibrillation, cardiac arrhythmia
  • Join ISVH

    Be part of the World's leading experts in vascular health by joining the International Society of Vascular Health (ISVH)

  • Testimonials

    "... I was impressed at the rapidity of publication from submission to final acceptance." Dr Edwin Thrower, PhD, Yale University