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Acute bilateral angle closure glaucoma induced by methazolamide

Authors Aref AA, Sayyad FE, Ayres B, Lee RK

Published Date February 2013 Volume 2013:7 Pages 279—282

DOI http://dx.doi.org/10.2147/OPTH.S41540

Received 13 December 2012, Accepted 9 January 2013, Published 11 February 2013

Ahmad A Aref,1,2 Fouad E Sayyad,2 Bernadete Ayres,2 Richard K Lee2

1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, 2Illinois Eye and Ear Infirmary, University of Illinois at Chicago School of Medicine, Chicago, IL, USA

Purpose: To report a case of bilateral acute myopia and angle closure glaucoma after ingestion of methazolamide.
Methods: An interventional case report of a 70-year-old male who developed bilateral, acute myopia and angle closure glaucoma after ingesting methazolamide tablets for the treatment of normal tension glaucoma.
Results: Bilateral anterior chamber shallowing associated with ciliary body edema, supraciliary effusions, and shallow posterior choroidal effusions were documented with slit-lamp photography and high-frequency ultrasonography. Near complete resolution of these signs after discontinuation of methazolamide were also documented.
Conclusion: Methazolamide may be associated with secondary myopia and angle closure glaucoma. Discontinuation of methazolamide leads to resolution of this process, as documented by slit-lamp photography and high-frequency ultrasonography.

Keywords: glaucoma, glaucoma pharmacology, angle closure glaucoma

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